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It was designed by the World Health Organization (WHO) and then adapted for the United States by the Centers for Medicare & Medicaid Services (CMS) and the National Center for Health Statistics (NCHS)

Before the promising therapeutic impact of miRNA can be realized, there are several challenges to be addressed, which include but not limited to targeted delivery of oligonucleotides to specific organs, tissues and cell types, poor bioavailability, limited tissue permeability (Stylianopoulos and Jain, 2013), potential drug resistance, and instability (Raemdonck et al., 2008)

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The impact of smoking on tuberculosis treatment outcomes: a meta-analysis

G., Ivanova, E